Enigma of the peripheral benzodiazepine receptor
…, I Bachman, R Shoukrun, Y Katz, L Veenman… - Pharmacological …, 1999 - ASPET
Benzodiazepines (BZs) 2 are used clinically as muscle relaxants, anticonvulsants, anxiolytics,
and sedativehypnotics. These effects are mediated primarily via the central BZ receptors (…
and sedativehypnotics. These effects are mediated primarily via the central BZ receptors (…
Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response
L Veenman, V Papadopoulos… - Current pharmaceutical …, 2007 - ingentaconnect.com
Due to its channel-like properties, the peripheral-type benzodiazepine receptor (PBR) has
been renamed the translocator protein (TSPO). In eukaryotes, the TSPO is primarily located in …
been renamed the translocator protein (TSPO). In eukaryotes, the TSPO is primarily located in …
The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development
L Veenman, M Gavish - Pharmacology & therapeutics, 2006 - Elsevier
Peripheral-type benzodiazepine receptors (PBRs) are abundant in the cardiovascular system.
In the cardiovascular lumen, PBRs are present in platelets, erythrocytes, lymphocytes, and …
In the cardiovascular lumen, PBRs are present in platelets, erythrocytes, lymphocytes, and …
VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis
L Veenman, Y Shandalov, M Gavish - Journal of bioenergetics and …, 2008 - Springer
The voltage dependent anion channel (VDAC), located in the outer mitochondrial membrane,
functions as a major channel allowing passage of small molecules and ions between the …
functions as a major channel allowing passage of small molecules and ions between the …
[HTML][HTML] Diagnostic and therapeutic potential of TSPO studies regarding neurodegenerative diseases, psychiatric disorders, alcohol use disorders, traumatic brain …
J Dimitrova-Shumkovska, L Krstanoski, L Veenman - Cells, 2020 - mdpi.com
Neuroinflammation and cell death are among the common symptoms of many central
nervous system diseases and injuries. Neuroinflammation and programmed cell death of the …
nervous system diseases and injuries. Neuroinflammation and programmed cell death of the …
CoCl2 Induces Apoptosis via the 18 kDa Translocator Protein in U118MG Human Glioblastoma Cells
S Zeno, M Zaaroor, S Leschiner, L Veenman… - Biochemistry, 2009 - ACS Publications
The 18 kDa translocator protein (TSPO), formerly known as the peripheral-type benzodiazepine
receptor, has been reported to be closely associated with the mitochondrial permeability …
receptor, has been reported to be closely associated with the mitochondrial permeability …
Peripheral-type benzodiazepine receptor density and in vitro tumorigenicity of glioma cell lines
L Veenman, E Levin, G Weisinger, S Leschiner… - Biochemical …, 2004 - Elsevier
The peripheral-type benzodiazepine receptor is found primarily on the outer mitochondrial
membrane and consists of three subunits: the 18kDa isoquinoline binding protein, the 32kDa …
membrane and consists of three subunits: the 18kDa isoquinoline binding protein, the 32kDa …
[HTML][HTML] Potential beneficial actions of fucoidan in brain and liver injury, disease, and intoxication—Potential implication of sirtuins
J Dimitrova-Shumkovska, L Krstanoski, L Veenman - Marine drugs, 2020 - mdpi.com
Increased interest in natural antioxidants has brought to light the fucoidans (sulfated
polysaccharides present in brown marine algae) as highly valued nutrients as well as effective and …
polysaccharides present in brown marine algae) as highly valued nutrients as well as effective and …
Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine
W Kugler, L Veenman, Y Shandalov… - Analytical Cellular …, 2008 - content.iospress.com
Background: We have previously shown that the anti-neoplastic agent erucylphosphohomocholine
(ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO), formerly …
(ErPC3) requires the mitochondrial 18 kDa Translocator protein (TSPO), formerly …
[HTML][HTML] Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in …
L Veenman, J Alten, K Linnemannstöns, Y Shandalov… - Apoptosis, 2010 - Springer
Erucylphosphohomocholine (ErPC3, Erufosine™) was reported previously to induce apoptosis
in otherwise highly apoptosis-resistant malignant glioma cell lines while sparing their non…
in otherwise highly apoptosis-resistant malignant glioma cell lines while sparing their non…