Protein degradation in cultured cells: II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1

M Wibo, B Poole - The Journal of cell biology, 1974 - rupress.org
… At the end of the experiment the washed cells were dissolved in 0.1 M NaOH-0.4% deoxycholate.
Total and 8% trichloroacetic acid-soluble radioactivity was measured on each sample …

PHARMACOLOGICAL EVIDENCE OF HYPOTENSIVE ACTIVITY OF MARRUBIUM VULGARE AND FOENICULUM VULGARE IN SPONTANEOUSLY …

SE Bardai, B Lyoussi, M Wibo… - Clinical and experimental …, 2001 - Taylor & Francis
… Relaxation to acetylcholine (10 −6 M) in Nad-precontracted arteries was used to check the
… Vandenberg and MCHamaide for their skilful technical assistance and Dr M.Philippe for her …

Analytical study of microsomes and isolated subcellular membranes from rat liver: I. Biochemical methods

…, D Thinès-Sempoux, M Wibo, M Robbi… - The Journal of cell …, 1974 - rupress.org
… with fl-glueuronidase for 30 rain at 37C in 0.2 M Na acetate-acetic acid buffer pH 5. Finally,
2 vol of 0.5 M Na carbonate-bicarbonate buffer were added and fluorescence was measured …

Analytical study of microsomes and isolated subcellular membranes from rat liver: II. Preparation and composition of the microsomal fraction

A Amar-Costesec, H Beaufay, M Wibo… - The Journal of Cell …, 1974 - rupress.org
… of subcellular fractions was performed as described by Wibo et al. (52). … M sucrose and in
Spinco rotor 40 excepted for references 8 and 37 : 0.88 M sucrose ; and reference 22:0.35 M

Comparative study of the antihypertensive activity of Marrubium vulgare and of the dihydropyridine calcium antagonist amlodipine in spontaneously hypertensive rat

S El Bardai, B Lyoussi, M Wibo… - Clinical and experimental …, 2004 - Taylor & Francis
Water extract of Marrubium vulgare is widely used as antihypertensive treatment in folk
medicine. We have compared the effect of 10‐week‐long treatment with amlodipine or …

The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare

S El Bardai, N Morel, M Wibo, N Fabre… - Planta …, 2003 - thieme-connect.com
… Preincubation of rat aorta with the cyclohexane fraction of M. vulgare water extract evoked
a dose-dependent inhibition of KCl-induced contraction while the aqueous fraction showed no …

Postnatal maturation of excitation-contraction coupling in rat ventricle in relation to the subcellular localization and surface density of 1, 4-dihydropyridine and …

M Wibo, G Bravo, T Godfraind - Circulation research, 1991 - Am Heart Assoc
… The washed pellet was resuspended in 0.25 M sucrose buffered at pH 7.4 with5 mM Tris-HCI
(… Wibo M: Mode of action of calcium antagonists: Voltagedependence and kinetics of drug-…

Analytical study of microsomes and isolated subcellular membranes from rat liver: III. Subfractionation of the microsomal fraction by isopycnic and differential …

…, D Thinès-Sempoux, M Wibo, M Robbi… - The Journal of Cell …, 1974 - rupress.org
Rat liver microsomal fractions have been equilibrated in various types of linear density gradients.
15 fractions were collected and assayed for 27 constituents. As a result of this analysis …

Protein degradation in cultured cells: the effect of fresh medium, fluoride, and iodoacetate on the digestion of cellular protein of rat fibroblasts

B Poole, M Wibo - Journal of Biological Chemistry, 1973 - Elsevier
Rat fibroblasts contain proteins of long and short half-lives, and these two populations can
be labeled selectively. Fresh medium contains a factor that inhibits the breakdown of those …

Characterisation of marrubenol, a diterpene extracted from Marrubium vulgare, as an L‐type calcium channel blocker

S El Bardai, M Wibo, MC Hamaide… - British journal of …, 2003 - Wiley Online Library
The objective of the present study was to investigate the mechanism of the relaxant activity
of marrubenol, a diterpenoid extracted from Marrubium vulgare. In rat aorta, marrubenol was …