Calcium-a life and death signal

MJ Berridge, MD Bootman, P Lipp - Nature, 1998 - nature.com
One of the most versatile and universal signalling agents in the human body is the calcium
ion, Ca2+. How does this simple ion act during cell birth, life and death, and how does it …

Inositol trisphosphate, a novel second messenger in cellular signal transduction

MJ Berridge, RF Irvine - Nature, 1984 - nature.com
There has recently been rapid progress in understanding receptors that generate intracellular
signals from inositol lipids. One of these lipids, phosphatidylinositol 4,5-bisphosphate, is …

The versatility and universality of calcium signalling

MJ Berridge, P Lipp, MD Bootman - Nature reviews Molecular cell …, 2000 - nature.com
The universality of calcium as an intracellular messenger depends on its enormous versatility.
Cells have a calcium signalling toolkit with many components that can be mixed and …

[HTML][HTML] Capacitative calcium entry.

MJ Berridge - Biochemical Journal, 1995 - ncbi.nlm.nih.gov
The original idea that calcium might enter cells through a capacitative mechanism was first
introduced by Jim Putney [1]. The somewhat surprising hypothesis was that calcium entry was …

Elementary and global aspects of calcium signalling

MJ Berridge - Journal of experimental biology, 1997 - journals.biologists.com
Calcium is a ubiquitous second messenger used to regulate a wide range of cellular processes.
This role in signalling has to be conducted against the rigid homeostatic mechanisms …

Cytosolic calcium oscillators

MJ Berridge, A Galione - The FASEB Journal, 1988 - Wiley Online Library
Many cells display oscillations in intracellular calcium resulting from the periodic release of
calcium from intracellular reservoirs. Frequencies are varied, but most oscillations have …

Inositol trisphosphate and calcium signalling

MJ Berridge - Nature, 1993 - nature.com
Inositol trisphosphate is a second messenger that controls many cellular processes by
generating internal calcium signals. It operates through receptors whose molecular and …

[PDF][PDF] Neuronal calcium signaling

MJ Berridge - Neuron, 1998 - cell.com
1962). Indeed, the two membranes are separated by a Calcium plays an important role in
regulating a great fuzzy material with a distinct periodicity reminiscent of variety of neuronal …

Calcium signalling: dynamics, homeostasis and remodelling

MJ Berridge, MD Bootman, HL Roderick - Nature reviews Molecular …, 2003 - nature.com
Ca 2+ is a highly versatile intracellular signal that operates over a wide temporal range to
regulate many different cellular processes. An extensive Ca 2+-signalling toolkit is used to …

The endoplasmic reticulum: a multifunctional signaling organelle

MJ Berridge - Cell calcium, 2002 - Elsevier
The endoplasmic reticulum (ER) is a multifunctional signaling organelle that controls a wide
range of cellular processes such as the entry and release of Ca 2+ , sterol biosynthesis, …