User profiles for Michal Heger

Michal Heger

Professor of photonanomedicine, Jiaxing University; PI, Utrecht University
Verified email at uu.nl
Cited by 7512

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - ASPET
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on the …

Physiological and biochemical basis of clinical liver function tests: a review

…, W de Graaf, GAA Nibourg, M Heger… - Annals of …, 2013 - journals.lww.com
Objective: To review the literature on the most clinically relevant and novel liver function
tests used for the assessment of hepatic function before liver surgery. Background: …

[HTML][HTML] Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections

…, R Qin, SAJ Zaat, E Breukink, M Heger - Journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Antibacterial photodynamic therapy (APDT) has drawn increasing attention from the scientific
society for its potential to effectively kill multidrug-resistant pathogenic bacteria and for its …

Transporters involved in the hepatic uptake of 99mTc-mebrofenin and indocyanine green

W de Graaf, S Häusler, M Heger, TM van Ginhoven… - Journal of …, 2011 - Elsevier
BACKGROUND & AIMS: 99m Tc-mebrofenin hepatobiliary scintigraphy (HBS) and the
indocyanine green (ICG) clearance test are used for the assessment of hepatic function before …

Mechanistic overview of reactive species-induced degradation of the endothelial glycocalyx during hepatic ischemia/reperfusion injury

RF van Golen, TM van Gulik, M Heger - Free Radical Biology and Medicine, 2012 - Elsevier
Endothelial cells are covered by a delicate meshwork of glycoproteins known as the glycocalyx.
Under normophysiological conditions the glycocalyx plays an active role in maintaining …

[PDF][PDF] Swarm intelligence-enhanced detection of non-small-cell lung cancer using tumor-educated platelets

…, JC Reijneveld, S Idema, J Killestein, M Heger… - Cancer cell, 2017 - cell.com
Blood-based liquid biopsies, including tumor-educated blood platelets (TEPs), have
emerged as promising biomarker sources for non-invasive detection of cancer. Here we …

[HTML][HTML] Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies

…, R Weijer, TM van Gulik, MR Hamblin, M Heger - Cancer and Metastasis …, 2015 - Springer
Photodynamic therapy (PDT) has emerged as a promising alternative to conventional
cancer therapies such as surgery, chemotherapy, and radiotherapy. PDT comprises the …

An overview of clinical and experimental treatment modalities for port wine stains

…, A Wolkerstorfer, KM Kelly, M Heger - Journal of the American …, 2012 - Elsevier
Port wine stains (PWS) are the most common vascular malformation of the skin, occurring in
0.3% to 0.5% of the population. Noninvasive laser irradiation with flashlamp-pumped pulsed …

The sterile immune response during hepatic ischemia/reperfusion

RF van Golen, TM van Gulik, M Heger - Cytokine & growth factor reviews, 2012 - Elsevier
Hepatic ischemia and reperfusion elicits an immune response that lacks a microbial constituent
yet poses a potentially lethal threat to the host. In this sterile setting, the immune system …

Sterile inflammation in hepatic ischemia/reperfusion injury: present concepts and potential therapeutics

…, PB Olthof, TM van Gulik, M Heger - Journal of …, 2013 - Wiley Online Library
Ischemia and reperfusion ( I / R ) injury is an often unavoidable consequence of major liver
surgery and is characterized by a sterile inflammatory response that jeopardizes the viability …