Striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific phosphatase that
modulates key signaling molecules involved in synaptic plasticity and neuronal function. …

Reduction of Aβ deposition is a major therapeutic strategy in Alzheimer's disease (AD). The
concentration of Aβ in the brain is modulated not only by Aβ production but also by its …

Background Antibodies against the Aß peptide clear Aß deposits when injected intracranially.
Deglycosylated antibodies have reduced effector functions compared to their intact …

Background Recombinant Adeno-associated viral (rAAV) vectors are an effective means of
gene delivery and gene transfer to the central nervous system and hold promise for the …

Alzheimer's disease (AD), first characterized in the early 20th century, is a common form of
dementia which can occur as a result of genetic mutations in the genes encoding presenilin 1, …

Alzheimer’s disease (AD), first characterized in the early 20 th century, is a common form of
dementia which can occur as a result of genetic mutations in the genes encoding presenilin 1…

In this paper, three distinct deep-learning models are presented for the participation in Track
1 of the IEEE GRSS Data Fusion Contest 2024. The objective of this challenge was to …

Experience alters brain structure, but the underlying mechanism remained unknown.
Structural plasticity reveals that brain function is encoded in generative changes to cells that …

In this dissertation I test the hypothesis on the origin of presidentialized parties that appear
as the specific historical and empirical model of party organization. The model of …

Thyroid follicular tumors can be challenging diagnostically and clinically, because the cytologic
and histologic features can be subtle and prognosis is also difficult to predict. In this study…