The influence of streptozotocin-induced diabetes mellitus on fluid and electrolyte handling in rats.

RA Hebden, SM Gardiner, T Bennett… - Clinical Science …, 1986 - europepmc.org
Intakes and urine outputs of fluid and electrolytes were measured daily in rats before, and
for 3 weeks after, induction of diabetes by intraperitoneal injection of streptozotocin (STZ; 60 …

Pressor sensitivities to vasopressin, angiotensin II, or methoxamine in diabetic rats

RA Hebden, T Bennett… - American Journal of …, 1987 - journals.physiology.org
We investigated the pressor sensitivities to vasopressin, angiotensin II, and methoxamine of
intact and ganglion-blocked rats that had been treated 21 days earlier with streptozotocin or …

Relationship between atrial granularity and release of atrial natriuretic factor in rats with diabetes mellitus

RA Hebden, ME Todd… - American Journal of …, 1989 - journals.physiology.org
We examined the effect of a 25% blood volume expansion on the release of atrial natriuretic
factor (ANF) in conscious Wistar rats (13-15 wk old) injected 6 wk earlier with streptozotocin (…

Association of DOCA hypertension with induction of atherosclerosis in rats with short-term diabetes mellitus

RA Hebden, ME Todd, C Tang… - American Journal of …, 1990 - journals.physiology.org
We investigated the effect of deoxycorticosterone acetate (DOCA)-induced hypertension on
plasma lipid and cholesterol levels and the development of vascular atherosclerotic changes …

Abnormal blood pressure recovery during ganglion blockade in diabetic rats

RA Hebden, T Bennett… - American Journal of …, 1987 - journals.physiology.org
The aim of the present study was to determine the extent to which vasopressin or the renin-angiotensin
system contributed to the recovery of blood pressure following acute hypotension …

Atrial structure and plasma ANF levels in rats with chronic diabetes mellitus

ME Todd, RA Hebden, B Gowen, C Tang… - Diabetes, 1990 - Am Diabetes Assoc
The effect of streptozocin-induced diabetes (STZ-D) on right atrial structure was investigated
in male Wistar rats. STZ (55 mg/kg) or saline (1 ml/kg) was administered by intravenous …

Concentration (s) of atrial natriuretic hormone in the plasma of rats with streptozotocin-induced diabetes mellitus

RA Hebden, JH McNeill - Life Sciences, 1988 - Elsevier
Blood was withdrawn from rats injected 1, 3, 6 and 12 weeks previously with the diabetogenic
agent streptozotocin (55 mg/kg, IV) or saline. Analysis of plasma showed that while the …

Cardiovascular function in the intact, streptozotocin-treated rat

RA Hebden - Experimental Models of Diabetes, 2018 - taylorfrancis.com
The study of integrated cardiovascular function in the intact, streptozotocin (STZ)-treated rat
is still in its infancy. An understanding of the potentially myriad effects of autonomic …

Effect of parathyroid hormone on myocardial bloodflow and infarct size following coronary artery occlusion in the dog.

RA Hebden, HJ Nathan - The Canadian Journal of Cardiology, 1994 - europepmc.org
Objective To investigate the cardioprotective effect of both the amino terminal of bovine
parathyroid hormone (bPTH-[1-34]) and human parathyroid hormone (hPTH-[1-84]) following …

Requirement for solutions with oncotic pressure to release ANF during blood volume expansion in conscious and anesthetized rats

RA Hebden, CL Tang, S Sanderson… - journal of Pharmacological …, 1990 - Elsevier
We examined the effect of a 30% blood volume expansion with either blood, isotonic saline,
or isotonic saline plus albumin on the release of immunoreactiveatrial natriuretic factor (IR-…