Modulation of vascular smooth muscle contraction by the endothelium

PM Vanhoutte, GM Rubanyi, VM Miller… - Annual Review of …, 1986 - annualreviews.org
The vascular endothelium is the layer of squamous epithelial cells that is in direct contact
with the blood. In addition to its other important functions, which include capillary transport, …

Vascular actions of estrogens: functional implications

VM Miller, SP Duckles - Pharmacological reviews, 2008 - ASPET
The impact of estrogen exposure in preventing or treating cardiovascular disease is
controversial. But it is clear that estrogen has important effects on vascular physiology and …

National trends and outcomes in isolated tricuspid valve surgery

…, YNV Reddy, CE Bennett, JM Stulak, VM Miller… - Journal of the American …, 2017 - jacc.org
Background : Severe isolated disease of the tricuspid valve (TV) is increasing and results in
intractable right heart failure. However, isolated TV surgery is rarely performed, and there …

[HTML][HTML] Effects of hormone therapy on cognition and mood in recently postmenopausal women: findings from the randomized, controlled KEEPS–cognitive and …

…, NM Dowling, W Wharton, JAE Manson, VM Miller… - PLoS …, 2015 - journals.plos.org
Background Menopausal hormone therapy (MHT) reportedly increases the risk of cognitive
decline in women over age 65 y. It is unknown whether similar risks exist for recently …

Sex differences and sex steroids in lung health and disease

EA Townsend, VM Miller, YS Prakash - Endocrine reviews, 2012 - academic.oup.com
Sex differences in the biology of different organ systems and the influence of sex hormones
in modulating health and disease are increasingly relevant in clinical and research areas. …

Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial

…, JAE Manson, GR Merriam, VM Miller… - Annals of internal …, 2014 - acpjournals.org
Background: Whether menopausal hormone therapy (MHT) protects against cardiovascular
disease (CVD) remains unclear. Objective: To assess atherosclerosis progression and CVD …

[HTML][HTML] Considering sex as a biological variable in preclinical research

LR Miller, C Marks, JB Becker, PD Hurn… - The FASEB …, 2017 - ncbi.nlm.nih.gov
In June 2015, the National Institutes of Health (NIH) released a Guide notice (NOT-OD-15-102)
that highlighted the expectation of the NIH that the possible role of sex as a biologic …

[HTML][HTML] Methodology for isolation, identification and characterization of microvesicles in peripheral blood

M Jayachandran, VM Miller, JA Heit… - Journal of immunological …, 2012 - Elsevier
RATIONALE: Analyses of circulating cell membrane-derived microvesicles (MV) have come
under scrutiny as potential diagnostic and prognostic biomarkers of disease. However, …

The effect of estrogen replacement therapy on plasma nitric oxide and endothelin-1 levels in postmenopausal women

PJM Best, PB Berger, VM Miller… - Annals of internal …, 1998 - acpjournals.org
Background: Estrogen replacement therapy (ERT) in postmenopausal women decreases
cardiac mortality and improves endothelial function. The endothelium regulates vascular tone …

Hormonal modulation of endothelial NO production

SP Duckles, VM Miller - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
Since the discovery of endothelium-derived relaxing factor and the subsequent identification
of nitric oxide (NO) as the primary mediator of endothelium-dependent relaxations, research …