Disseminated intravascular coagulation is a frequent complication of sepsis. Coagulation
activation, inhibition of fibrinolysis, and consumption of coagulation inhibitors lead to a …

C1-esterase inhibitor (C1-Inh) therapy was introduced in clinical medicine about 25 years ago
as a replacement therapy for patients with hereditary angioedema caused by a deficiency …

Clinical outcome studies have shown that it is safe to withhold anticoagulant therapy in patients
with suspected pulmonary embolism (PE) who have a negative D-dimer result and a low …

Activated mast cells trigger edema in allergic and inflammatory disease. We report a paracrine
mechanism by which mast cell-released heparin increases vascular permeability in vivo. …

… Zeerleder, Sacha MD; Zwart, Bas MD; Wuillemin, Walter A. MD, PhD; Aarden, Lucien A.
PhD; Groeneveld, AB Johan MD; Caliezi, Christoph MD; van Nieuwenhuijze, Annemarie EM; …

… The dysfunctional F XII molecule (F XII Washington DC) of one of these individuals has been
purified and partially charactenzed by Saito and Scialla (43), and the postulated defect near …

… Walter Wuillemin and Maurice Redondo were responsible for patient data and blood
collection and did the statistical analysis. The paper was mainly written by Beat Meyer, but all …

… TEN CATE 6 7 , PH REITSMA 6 , WA WUILLEMIN 8 , B. LÄMMLE 1 … Lämmle and WA
Wuillemin. S. Zeerleder and WA Wuillemin recruited patients and collected clinical data. JA Kremer …

OBJECTIVES We sought to compare the inhibitory effects of the combination of two doses of
aspirin plus clopidogrel with either drug alone on platelet aggregation and activation. …

INTRODUCTION: Rivaroxaban (RXA) is licensed for prophylaxis of venous thromboembolism
after major orthopaedic surgery of the lower limbs. Currently, no test to quantify RXA in …