The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea‐pig ileum

WDM Paton - British journal of pharmacology and …, 1957 - Wiley Online Library
Morphine depresses the twitch and tetanus of stimulated guinea‐pig ileum by reducing
acetylcholine released from cholinergic nerve endings. Acetylcholine output per shock falls to …

Compound 48/80: a potent histamine liberator

WDM Paton - British journal of pharmacology and chemotherapy, 1951 - ncbi.nlm.nih.gov
… Since then, Feldberg and Paton (1951) haveused this substance to demonstrate the release
of histamine from the cat's isolated perfused skin preparation. … The delayed depressor …

The inhibitory action of noradrenaline and adrenaline on acetylcholine output by guinea‐pig ileum longitudinal muscle strip

WDM Paton, ES Vizi - British journal of pharmacology, 1969 - Wiley Online Library
… of sympathetic innervation because with the present method of preparing the strips a greater
number of blood vessels may have been preserved than in the experiments of Paton & Zar. …

The margin of safety of neuromuscular transmission

WDM Paton, DR Waud - The Journal of Physiology, 1967 - Wiley Online Library
… from that originally used by Burns & Paton (1951) and Douglas & Paton (1954), as a result
of … WDM PATON AND DR WAUD electrodes which could detect much smaller changes than …

The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors

WDM Paton, HP Rang - … of the Royal Society of London …, 1965 - royalsocietypublishing.org
Paton measured the time taken for the response to a given test dose to fall to a certain
level, which enabled the dose ratio to be measured without reference to the dose-response …

The pressure reversal of general anesthesia and the critical volume hypothesis

KW Miller, WDM Paton, RA Smith, EB Smith - Molecular Pharmacology, 1973 - ASPET
The anesthetic potencies (ED 50 ) of four gaseous anesthetics and five liquid anesthetics
were first determined in newts, using the abolition of righting reflex measured by the rolling …

Preliminary experiments on the chemistry and pharmacology of cannabis

EW Gill, WDM Paton, RG Pertwee - Nature, 1970 - nature.com
are not a result of cytoplasmic contamination. For Page 1 134 or other counting anomalies
which might occur at specific regions of the gel. Other control cxperiments have established that …

A theory of drug action based on the rate of drug-receptor combination

WDM Paton - Proceedings of the Royal Society of …, 1961 - royalsocietypublishing.org
… Thesleff 1957); and the type of response typified by nicotine on ganglia, where a vigorous
excitation rapidly fades, to be replaced by an apparently pure competi tive antagonism (Paton

The pharmacological actions of polymethylene bistrimethylammonium salts

WDM Paton, EJ Zaimis - British journal of pharmacology and …, 1949 - ncbi.nlm.nih.gov
… which a fine adjustable leak was provided, and measuring the pressure within it by a sensitive
tambour; later measurements were made with the respiration recorder described by Paton

The origin of acetylcholine released from guinea‐pig intestine and longitudinal muscle strips

WDM Paton, MA Zar - The Journal of Physiology, 1968 - Wiley Online Library
… Electron microscopically, only two, scantily myelinated, fibres have been seen which might
have such an origin (WDM Paton, unpublished), although in almost' every section fibres in the …