Review ArticleReview
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
Ilia J. Elenkov, Ronald L. Wilder, George P. Chrousos and E. Sylvester Vizi
Pharmacological Reviews December 2000, 52 (4) 595-638;
Ilia J. Elenkov
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Ronald L. Wilder
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George P. Chrousos
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E. Sylvester Vizi
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Review ArticleReview
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
Ilia J. Elenkov, Ronald L. Wilder, George P. Chrousos and E. Sylvester Vizi
Pharmacological Reviews December 1, 2000, 52 (4) 595-638;
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- Article
- Abstract
- I. Introduction
- II. Anatomy and Physiology of the Autonomic Nervous System
- III. Autonomic/Sympathetic Innervation of Lymphoid Organs: Nonsynaptic Communication
- IV. Nonsynaptic Release of Norepinephrine in Lymphoid Organs: Presynaptic Modulation and Effect of Drugs
- V. Systemic and Local Effects of Cytokines on Sympathetic Nervous System Activity
- VI. Expression of Adrenoreceptors on Lymphoid Cells: Signal Transduction
- VII. Role of Sympathetic Innervation in Immune System Development and Hematopoiesis
- VIII. Sympathetic Control of Lymphocyte Traffic and Circulation
- IX. Modulation of Lymphocyte Proliferation and K+Channel Conductance
- X. Modulation of cellular and humoral immunity by catecholamines
- XI. Role of Growth Factors in Sympathetic Nervous System Development and Modulation of the Immune Response
- XII. Physiologic Control of the Sympathetic-Immune Interface: β-Adrenergic Receptor Expression, Coupling, and Desensitization
- XIII. Clinical Implications
- XIV. Pharmacological Manipulation of the Sympathetic-Immune Interface
- XV. Conclusions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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