Research ArticleArticle
International Union of Pharmacology. XLV. Classification of the Kinin Receptor Family: from Molecular Mechanisms to Pathophysiological Consequences
L. M. Fredrik Leeb-Lundberg, Francois Marceau, Werner Müller-Esterl, Douglas J. Pettibone and Bruce L. Zuraw
Pharmacological Reviews March 2005, 57 (1) 27-77; DOI: https://doi.org/10.1124/pr.57.1.2
L. M. Fredrik Leeb-Lundberg
Division of Cellular and Molecular Pharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden (L.M.F.L.-L.); Centre de Recherche, Centre Hospitalier Universitaire de Quebec, Quebec, Canada (F.M.); Institute of Biochemistry II, Johann Wolfgang Goethe University School of Medicine, Frankfurt, Germany (W.M.-E.); Departments of Medicinal Chemistry and Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (D.J.P.); and Department of Medicine, Veterans Affairs Medical Center and University of California, San Diego, California (B.L.Z.)
Francois Marceau
Division of Cellular and Molecular Pharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden (L.M.F.L.-L.); Centre de Recherche, Centre Hospitalier Universitaire de Quebec, Quebec, Canada (F.M.); Institute of Biochemistry II, Johann Wolfgang Goethe University School of Medicine, Frankfurt, Germany (W.M.-E.); Departments of Medicinal Chemistry and Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (D.J.P.); and Department of Medicine, Veterans Affairs Medical Center and University of California, San Diego, California (B.L.Z.)
Werner Müller-Esterl
Division of Cellular and Molecular Pharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden (L.M.F.L.-L.); Centre de Recherche, Centre Hospitalier Universitaire de Quebec, Quebec, Canada (F.M.); Institute of Biochemistry II, Johann Wolfgang Goethe University School of Medicine, Frankfurt, Germany (W.M.-E.); Departments of Medicinal Chemistry and Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (D.J.P.); and Department of Medicine, Veterans Affairs Medical Center and University of California, San Diego, California (B.L.Z.)
Douglas J. Pettibone
Division of Cellular and Molecular Pharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden (L.M.F.L.-L.); Centre de Recherche, Centre Hospitalier Universitaire de Quebec, Quebec, Canada (F.M.); Institute of Biochemistry II, Johann Wolfgang Goethe University School of Medicine, Frankfurt, Germany (W.M.-E.); Departments of Medicinal Chemistry and Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (D.J.P.); and Department of Medicine, Veterans Affairs Medical Center and University of California, San Diego, California (B.L.Z.)
Bruce L. Zuraw
Division of Cellular and Molecular Pharmacology, Department of Experimental Medical Science, Lund University, Lund, Sweden (L.M.F.L.-L.); Centre de Recherche, Centre Hospitalier Universitaire de Quebec, Quebec, Canada (F.M.); Institute of Biochemistry II, Johann Wolfgang Goethe University School of Medicine, Frankfurt, Germany (W.M.-E.); Departments of Medicinal Chemistry and Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (D.J.P.); and Department of Medicine, Veterans Affairs Medical Center and University of California, San Diego, California (B.L.Z.)
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Research ArticleArticle
International Union of Pharmacology. XLV. Classification of the Kinin Receptor Family: from Molecular Mechanisms to Pathophysiological Consequences
L. M. Fredrik Leeb-Lundberg, Francois Marceau, Werner Müller-Esterl, Douglas J. Pettibone and Bruce L. Zuraw
Pharmacological Reviews March 1, 2005, 57 (1) 27-77; DOI: https://doi.org/10.1124/pr.57.1.2
Research ArticleArticle
International Union of Pharmacology. XLV. Classification of the Kinin Receptor Family: from Molecular Mechanisms to Pathophysiological Consequences
L. M. Fredrik Leeb-Lundberg, Francois Marceau, Werner Müller-Esterl, Douglas J. Pettibone and Bruce L. Zuraw
Pharmacological Reviews March 1, 2005, 57 (1) 27-77; DOI: https://doi.org/10.1124/pr.57.1.2
Jump to section
- Article
- Abstract
- I. A Short History of Kinins and Their Receptors
- II. Pharmacological Classification of Kinin Receptor Subtypes
- III. Structural Aspects of Kinin Receptors and Their Genes
- IV. Molecular and Cellular Aspects of Kinin Receptor Signaling and Regulation
- V. Long-Term Regulation of Kinin Receptors by Proinflammatory Factors
- VI. Distribution and Pathophysiological Function of Kinin Receptors
- VII. Kinin Receptors and Human Disease
- VIII. Kinin Receptors and Drug Development
- IX. Epilogue
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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