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Table of Contents

July 01, 2012; Volume 64,Issue 3

IUPHAR Nomenclature Report

Review Articles

  • Organic Anion Transporters and Their Implications in Pharmacotherapy
    Arian Emami Riedmaier, Anne T. Nies, Elke Schaeffeler and Matthias Schwab
    Markku Koulu, ASSOCIATE EDITOR, Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany (A.E.R., A.T.N., E.S., M.S.); and Department of Clinical Pharmacology, Institute of Experimental and Clinical Pharmacology and Toxicology, University Hospital, Tuebingen, Germany (M.S.)
    Pharmacological Reviews July 2012, 64 (3) 421-449; DOI: https://doi.org/10.1124/pr.111.004614
  • Pharmacology and Therapeutics of Bronchodilators
    Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
    David R. Sibley, ASSOCIATE EDITOR, Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
    Pharmacological Reviews July 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580
  • Physical and Chemical Strategies for Therapeutic Delivery by Using Polymeric Nanoparticles
    José M. Morachis, Enas A. Mahmoud and Adah Almutairi
    Paul A. Insel, ASSOCIATE EDITOR, Skaggs School of Pharmacy & Pharmaceutical Sciences (J.M.M., E.A.M., A.A.), Department of Materials Science and Engineering (A.A.), and Department of NanoEngineering (A.A.), University of California San Diego, La Jolla, California
    Pharmacological Reviews July 2012, 64 (3) 505-519; DOI: https://doi.org/10.1124/pr.111.005363
  • Aldehyde Dehydrogenase Inhibitors: a Comprehensive Review of the Pharmacology, Mechanism of Action, Substrate Specificity, and Clinical Application
    Vindhya Koppaka, David C. Thompson, Ying Chen, Manuel Ellermann, Kyriacos C. Nicolaou, Risto O. Juvonen, Dennis Petersen, Richard A. Deitrich, Thomas D. Hurley and Vasilis Vasiliou
    David R. Sibley, ASSOCIATE EDITOR, Departments of Pharmaceutical Sciences (V.K., Y.C., D.P., V.V.) and Clinical Pharmacy (D.C.T.), School of Pharmacy, and Department of Pharmacology, School of Medicine (R.A.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Chemistry (M.E., K.C.N.) and Skaggs Institute of Chemical Biology (K.C.N.), the Scripps Research Institute, La Jolla, California; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California (K.C.N.); School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (R.O.J.); and Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana (T.D.H.)
    Pharmacological Reviews July 2012, 64 (3) 520-539; DOI: https://doi.org/10.1124/pr.111.005538
  • Molecular Mechanisms Regulating the Vascular Prostacyclin Pathways and Their Adaptation during Pregnancy and in the Newborn
    Batoule H. Majed and Raouf A. Khalil
    Christopher J. Garland, ASSOCIATE EDITOR, Vascular Surgery Research Laboratory, Division of Vascular and Endovascular Surgery, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts
    Pharmacological Reviews July 2012, 64 (3) 540-582; DOI: https://doi.org/10.1124/pr.111.004770
  • The Pharmacological Treatment of Pulmonary Arterial Hypertension
    Lyn R. Frumkin
    Clive Page, ASSOCIATE EDITOR, Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California
    Pharmacological Reviews July 2012, 64 (3) 583-620; DOI: https://doi.org/10.1124/pr.111.005587
  • Pharmacology for the Treatment of Premature Ejaculation
    François Giuliano and Pierre Clèment
    Ulf Simonsen, ASSOCIATE EDITOR, Neuro-Uro-Andrology, Physical Medicine and Rehabilitation Department, Raymond Poincaré Hospital, Assistance Publique-Hopitaux de Paris, Garches, France (F.G.); Pelvipharm Laboratories, Orsay, France (F.G., P.C.); and Equipe d'Accueil 4501, University of Versailles St-Quentin-en-Yvelines, Versailles, France (F.G., P.C.)
    Pharmacological Reviews July 2012, 64 (3) 621-644; DOI: https://doi.org/10.1124/pr.111.004952
  • G-Protein-Coupled Receptors in Adult Neurogenesis
    Van A. Doze and Dianne M. Perez
    David R. Sibley, ASSOCIATE EDITOR, Department of Pharmacology, Physiology and Therapeutics, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota (V.A.D.); and Department of Molecular Cardiology, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio (D.M.P.)
    Pharmacological Reviews July 2012, 64 (3) 645-675; DOI: https://doi.org/10.1124/pr.111.004762
  • Classification, Functions, and Clinical Relevance of Extracellular Vesicles
    Edwin van der Pol, Anita N. Böing, Paul Harrison, Augueste Sturk and Rienk Nieuwland
    Mark P. Mattson, ASSOCIATE EDITOR, Departments of Clinical Chemistry (E.v.d.P., A.B., A.S., R.N.) and Biomedical Engineering and Physics (E.v.d.P.), Academic Medical Centre of the University of Amsterdam, Amsterdam, the Netherlands; and Oxford Haemophilia & Thrombosis Centre, Churchill Hospital, Oxford, United Kingdom (P.H.)
    Pharmacological Reviews July 2012, 64 (3) 676-705; DOI: https://doi.org/10.1124/pr.112.005983
  • Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes
    Ding-Wu Shen, Lynn M. Pouliot, Matthew D. Hall and Michael M. Gottesman
    David R. Sibley, ASSOCIATE EDITOR, Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    Pharmacological Reviews July 2012, 64 (3) 706-721; DOI: https://doi.org/10.1124/pr.111.005637
  • Human Experimental Pain Models for Assessing the Therapeutic Efficacy of Analgesic Drugs
    Anne Estrup Olesen, Trine Andresen, Camilla Staahl and Asbjørn Mohr Drewes
    Ulf Simonsen, ASSOCIATE EDITOR, Mech-Sense, Department of Gastroenterology & Hepatology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark (A.E.O., T.A., A.M.D.); Grünenthal GmBH, R & D, Aachen, Germany (C.S.); and Center for Sensory-Motor Interaction, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark (A.M.D.)
    Pharmacological Reviews July 2012, 64 (3) 722-779; DOI: https://doi.org/10.1124/pr.111.005447
  • Thinking Outside the Cleft to Understand Synaptic Activity: Contribution of the Cystine-Glutamate Antiporter (System xc−) to Normal and Pathological Glutamatergic Signaling
    Richard Bridges, Victoria Lutgen, Doug Lobner and David A. Baker
    Lynette C. Daws, ASSOCIATE EDITOR, Center for Structural and Functional Neuroscience, Department of Biomedical and Pharmaceutical Sciences, University of Montana, Missoula, Montana (R.B.); and Department of Biomedical Sciences, Marquette University, Milwaukee, Wisconsin (V.L., D.L., D.A.B.)
    Pharmacological Reviews July 2012, 64 (3) 780-802; DOI: https://doi.org/10.1124/pr.110.003889
  • The Dual Role of Pharmacogenetics in HIV Treatment: Mutations and Polymorphisms Regulating Antiretroviral Drug Resistance and Disposition
    Veronique Michaud, Tamara Bar-Magen, Jacques Turgeon, David Flockhart, Zeruesenay Desta and Mark A. Wainberg
    Theresa A. Shapiro, ASSOCIATE EDITOR, McGill University AIDS Centre, Lady Davis Institute for Medical Research, Jewish General Hospital, Montréal, Québec, Canada (V.M., T.B.-M., M.A.W.); Division of Clinical Pharmacology, Indiana University School of Medicine, Indianapolis, Indiana (V.M., D.F., Z.D.); Faculté de Pharmacie, Université de Montréal, Montréal, Québec, Canada (V.M., J.T.); Laboratory of Molecular Biology, Infectious Diseases Department, Hospital Carlos III, Madrid, Spain (T.B.-M.); and Centre de recherche du Centre hospitalier de l'Université de Montréal, Montréal, Québec, Canada (J.T.)
    Pharmacological Reviews July 2012, 64 (3) 803-833; DOI: https://doi.org/10.1124/pr.111.005553
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