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History
- Published online September 28, 2012.
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- Earlier version (September 10, 2012 - 11:01).
- You are viewing the most recent version of this article.
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U.S. Government work not protected by U.S. copyright
Author Information
- Qiang Ma and
- Xiaoqing He
- David R. Sibley, ASSOCIATE EDITOR
- Address correspondence to:
Q. Ma, Mailstop 3014, 1095 Willowdale Road, Morgantown, WV 26505. E-mail: qam1{at}cdc.gov
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- Article
- Abstract
- I. Introduction
- II. The Nuclear Factor Erythroid 2-Related Factor 2–Antioxidant Response Element (Nrf2-ARE) Pathway: Finding the Xenobiotic-Activated Receptor
- III. Mechanism of Nuclear Factor Erythroid 2-Related Factor 2 Regulation: Insights from Structure
- IV. Nuclear Factor Erythroid 2-Related Factor 2 Signaling in Disease and Toxicity: Expecting the Unexpected
- V. Genetics and Cancer Mutation: Revealing the Perilous Side of Nuclear Factor Erythroid 2-Related Factor 2 Signaling Activation
- VI. Targeting the Nuclear Factor Erythroid 2-Related Factor 2 Signaling-Antioxidant Response Element Pathway for Drug Development: Going beyond the Promise
- VII. Conclusion
- Authorship Contributions
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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