Review ArticleReview Article
Open Access
Pharmacology of Heparin and Related Drugs: An Update
John Hogwood, Barbara Mulloy, Rebeca Lever, Elaine Gray and Clive P. Page
Lynette Daws, ASSOCIATE EDITOR
Pharmacological Reviews March 2023, 75 (2) 328-379; DOI: https://doi.org/10.1124/pharmrev.122.000684
John Hogwood
Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King’s College London, London, United Kingdom (B.M., E.G., C.P.P.); National Institute for Biological Standards and Control, South Mimms, Hertfordshire, United Kingdom (J.H., E.G.) and School of Pharmacy, University College London, London, United Kingdom (R.L.)
Barbara Mulloy
Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King’s College London, London, United Kingdom (B.M., E.G., C.P.P.); National Institute for Biological Standards and Control, South Mimms, Hertfordshire, United Kingdom (J.H., E.G.) and School of Pharmacy, University College London, London, United Kingdom (R.L.)
Rebeca Lever
Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King’s College London, London, United Kingdom (B.M., E.G., C.P.P.); National Institute for Biological Standards and Control, South Mimms, Hertfordshire, United Kingdom (J.H., E.G.) and School of Pharmacy, University College London, London, United Kingdom (R.L.)
Elaine Gray
Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King’s College London, London, United Kingdom (B.M., E.G., C.P.P.); National Institute for Biological Standards and Control, South Mimms, Hertfordshire, United Kingdom (J.H., E.G.) and School of Pharmacy, University College London, London, United Kingdom (R.L.)
Clive P. Page
Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King’s College London, London, United Kingdom (B.M., E.G., C.P.P.); National Institute for Biological Standards and Control, South Mimms, Hertfordshire, United Kingdom (J.H., E.G.) and School of Pharmacy, University College London, London, United Kingdom (R.L.)
Lynette Daws
Roles: ASSOCIATE EDITOR
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In this issue
Review ArticleReview Article
Update on the Pharmacology of Heparin and Related Drugs
John Hogwood, Barbara Mulloy, Rebeca Lever, Elaine Gray and Clive P. Page
Pharmacological Reviews March 1, 2023, 75 (2) 328-379; DOI: https://doi.org/10.1124/pharmrev.122.000684
Jump to section
- Article
- Abstract
- I. Introduction
- II. Structural Aspects of Heparin and Related Drugs
- III. Analysis of Heparin
- IV. Molecular Interactions of Heparin
- V. Mechanism of Anticoagulant Action
- VI. Clinical Use of Heparin as an Anticoagulant/Antithrombotic
- VII. Nonanticoagulant Effects of Heparin
- VIII. Heparin in Biomaterials and Regenerative Medicine
- IX. Novel Formulations and Drug Delivery Technology for Heparin
- X. Novel Drugs Based on the Nonanticoagulant Actions of Heparin
- XI. Summary
- Acknowledgments
- Authorship Contributions
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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